Biotechnological Production of Vaccines
Biology ⇒ Biotechnology and Applications
Biotechnological Production of Vaccines starts at 11 and continues till grade 12.
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Describe one ethical concern associated with the use of genetically modified organisms (GMOs) in vaccine production.
Describe the main steps involved in producing a recombinant protein vaccine using E. coli as a host.
Describe the role of bioreactors in the large-scale production of vaccines.
Describe the role of reverse vaccinology in the development of new vaccines.
Explain the difference between live attenuated vaccines and recombinant subunit vaccines.
Explain the principle behind mRNA vaccines and how they are produced using biotechnology.
Explain why adjuvants are often added to biotechnologically produced vaccines.
Explain why quality control is important in the production of biotechnological vaccines.
Which of the following is a challenge in the production of recombinant vaccines?
(1) High yield of antigen
(2) Ensuring correct protein folding
(3) Low cost of production
(4) No need for purification
Which of the following is a key step in the purification of recombinant vaccine antigens?
(1) Electrophoresis
(2) Chromatography
(3) PCR amplification
(4) DNA sequencing
Which of the following is a limitation of DNA vaccines?
(1) They are always highly immunogenic in humans.
(2) There is a risk of integration into the host genome.
(3) They cannot be produced in large quantities.
(4) They require live virus cultures.
Which of the following is a major advantage of DNA vaccines over traditional vaccines?
(1) They require cold storage.
(2) They can induce both humoral and cellular immunity.
(3) They are always more expensive.
(4) They use live pathogens.
Fill in the blank: The _______ approach involves using computer algorithms to predict antigenic sites for vaccine design.
Fill in the blank: The _______ method is used to introduce DNA into plant cells for the production of edible vaccines.
Fill in the blank: The _______ system is often used for the expression of complex eukaryotic proteins for vaccine production.
Fill in the blank: The _______ technique is used to confirm the expression of recombinant proteins in host cells during vaccine production.
True or False: All biotechnologically produced vaccines require cold chain storage.
True or False: All vaccines produced using biotechnology are live vaccines.
True or False: Biotechnology allows for the production of vaccines that are free from animal-derived components.
True or False: Edible vaccines are produced by genetically modifying plants to express antigenic proteins.
