Gene Therapy
Biology ⇒ Biotechnology and Applications
Gene Therapy starts at 12 and continues till grade 12.
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Describe one limitation of using viral vectors in gene therapy.
Describe one way gene therapy can be used in cancer treatment.
Describe the main goal of gene silencing in gene therapy.
Describe the role of regulatory agencies in gene therapy.
Explain the difference between somatic and germline gene therapy.
Explain the importance of targeting specificity in gene therapy.
Explain why gene therapy is considered a potential cure for genetic disorders.
A patient with a genetic disorder caused by a single base mutation is being considered for gene therapy. Explain why base editing might be preferred over traditional gene addition therapy in this case.
Which of the following diseases has been a target for gene therapy clinical trials?
(1) Cystic fibrosis
(2) Diabetes
(3) Influenza
(4) Malaria
Which of the following is a challenge in targeting gene therapy to the central nervous system?
(1) Blood-brain barrier
(2) High cell turnover
(3) Lack of target cells
(4) None of the above
Which of the following is a limitation of gene therapy for treating brain disorders?
(1) Difficulty crossing the blood-brain barrier
(2) High cell turnover
(3) Lack of target cells
(4) None of the above
Which of the following is a non-viral method of gene delivery?
(1) Adenovirus
(2) Retrovirus
(3) Liposome
(4) Lentivirus
Fill in the blank: _______ gene therapy aims to introduce a gene that produces a therapeutic protein.
Fill in the blank: In vivo gene therapy delivers the gene _______ the patient's body.
Fill in the blank: The first approved gene therapy treatment in the world was for _______.
Fill in the blank: The most common vectors used in gene therapy are _______.
True or False: All gene therapy involves the use of recombinant DNA technology.
True or False: All gene therapy treatments are permanent.
True or False: Ex vivo gene therapy involves modifying cells outside the body and then reintroducing them.
True or False: Gene therapy can be used to enhance normal human traits such as intelligence or strength.
