Epigenetics
Biology ⇒ Genetics and Heredity
Epigenetics starts at 11 and continues till grade 12.
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See sample questions for grade 11
A scientist observes that a gene is not expressed in liver cells but is active in brain cells. Explain how epigenetic mechanisms could account for this difference.
Describe how epigenetic therapy might be used to treat cancer.
Describe how histone modification can affect gene expression.
Describe one way in which epigenetics is important in development.
Describe the process of genomic imprinting.
Describe the role of DNA methylation in gene silencing.
Explain how environmental factors can lead to epigenetic changes.
A scientist observes that a gene is not expressed in liver cells but is active in brain cells. Explain how epigenetic mechanisms could account for this difference.
Which enzyme is responsible for adding methyl groups to DNA? (1) DNA polymerase (2) DNA methyltransferase (3) RNA polymerase (4) Histone deacetylase
Which of the following best describes the role of chromatin remodeling in epigenetics? (1) It changes the DNA sequence (2) It alters the accessibility of DNA to transcription machinery (3) It repairs DNA damage (4) It synthesizes new proteins
Which of the following diseases is associated with abnormal epigenetic regulation? (1) Sickle cell anemia (2) Prader-Willi syndrome (3) Cystic fibrosis (4) Down syndrome
Which of the following is a common site for DNA methylation? (1) Adenine (2) Cytosine (3) Guanine (4) Thymine
Fill in the blank: Epigenetic modifications that are erased and re-established during gamete formation are called __________.
Fill in the blank: The addition of a methyl group to DNA, often at cytosine bases, is called __________.
Fill in the blank: The enzyme that removes acetyl groups from histones is called __________.
Fill in the blank: The process by which a cell becomes specialized in structure and function is called __________, and is regulated by epigenetic mechanisms.
True or False: All cells in an organism have the same epigenetic marks.
True or False: All epigenetic changes are erased during the formation of gametes.
True or False: Environmental factors such as diet and stress can influence epigenetic modifications.
True or False: Epigenetic changes always result in permanent changes to gene expression.
