Genetic Disorders
Biology ⇒ Genetics and Heredity
Genetic Disorders starts at 9 and continues till grade 12.
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See sample questions for grade 9
Describe how gene therapy might be used to treat a genetic disorder.
Describe one ethical issue related to genetic testing for disorders.
Describe one way genetic disorders can be diagnosed before birth.
Describe the inheritance pattern of thalassemia.
Describe the main difference between monogenic and polygenic genetic disorders.
Explain the difference between autosomal dominant and autosomal recessive genetic disorders.
Explain why carriers of sickle cell anemia are often resistant to malaria.
Explain why consanguineous marriages (marriage between close relatives) increase the risk of genetic disorders.
Which of the following genetic disorders is caused by a dominant allele?
(1) Cystic fibrosis
(2) Huntington's disease
(3) Sickle cell anemia
(4) Tay-Sachs disease
Which of the following is a chromosomal disorder?
(1) Sickle cell anemia
(2) Down syndrome
(3) Cystic fibrosis
(4) Hemophilia
Which of the following is a monogenic disorder?
(1) Diabetes
(2) Sickle cell anemia
(3) Heart disease
(4) Cancer
Which of the following is a sex-linked genetic disorder?
(1) Sickle cell anemia
(2) Hemophilia
(3) Cystic fibrosis
(4) Down syndrome
Cystic fibrosis is caused by a mutation in a gene located on chromosome _______.
Fill in the blank: A person with one normal allele and one mutated allele for a recessive disorder is called a _______.
Fill in the blank: Hemophilia is more common in _______ (males/females) because it is an X-linked disorder.
Fill in the blank: Tay-Sachs disease is most commonly found in people of _______ descent.
True or False: All children of a parent with an autosomal dominant disorder will inherit the disorder.
True or False: All genetic disorders are present at birth.
True or False: All mutations in DNA lead to genetic disorders.
True or False: Down syndrome is caused by an extra copy of chromosome 21.
